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个人简历
2006年09月–2010年06月,安徽大学,化学化工学院,化学专业,获理学学士学位;
2010年09月–2013年06月,安徽大学,化学化工学院,有机化学专业,获理学硕士学位,导师:周虹屏教授;
2013年09月–2016年09月,法国里昂高等师范,化学专业,获博士学位,导师:Chantal Andraud教授;
2016年11月–2020年06月,香港科技大学,化学系,博士后,合作导师:唐本忠教授;
2020年07月–至今,合肥工业大学,金沙威尼斯欢乐人城,黄山青年学者,研究员。
主要研究领域、方向
硕士生招生专业:化学(学术型);化学工程(专业型)
主要研究方向:新型有机发光材料的设计开发、机理研究及探索其在生物医学、刺激响应材料、光电器件等领域方面的应用。
主讲本科生课程:《有机化学C》《有机结构理论》《基础化学》
研究成果(代表性成果)
迄今已在国际重要学术期刊上发表SCI学术论文四十余篇,以第一作者(包括共一)和通讯作者发表论文二十余篇,包括Adv. Mater.、ACS Nano、Adv. Funct. Mater.、Nano Today、Mater. Horiz.、Chem. Sci.、Biomaterials、Appl. Mater. Interfaces等。其中14篇论文影响因子大于10,3篇论文入选ESI高被引。部分研究成果被ACS Noteworthy Chemistry、MaterialsViews China等国内外知名学术媒体作为亮点报道。入选2022年安徽省级人才计划(青年项目)。多次受邀在国际/国内学术会议上作邀请报告。
目前承担科研项目
(1)国家自然科学基金青年项目(22105057),2022.01-2024.12,主持;
(2)安徽省留学回国人员创新创业计划(2022LCX022),2022.11-2023.11,主持;
(3)中央高校基本科研业务费项目(JZ2023HGTB0228),2023.04-2024.12,主持;
(4)无机有机杂化功能材料化学安徽省重点实验室开放课题,2021.01-2022.12,主持;
(5)合肥工业大学“黄山青年学者”引进人才启动基金,2020.07-2023.07,主持。
获奖及专利情况
获奖:
(1)安徽省自然科学三等奖(4/5),2020年;
(2)安徽省第三届普通高等学校大学生化学竞赛“优秀指导教师”;
(3)指导学生参加安徽省第三届普通高等学校大学生化学竞赛获一等奖,第一指导老师;
专利:
(1)郑正,曹辉,苟学鑫,杨天雨,具有聚集诱导发光性质的化合物及其制备方法和应用,中国,ZL202211248006.1,已授权;
(2)唐本忠,郑正,用于单线态氧生成与癌症消融的荧光探针,中国,ZL202080013949.9,已授权;
(3)唐本忠,郑正,具有强双光子吸收的近红外化合物的制备及应用,中国,ZL201910265433.2,已授权。
著作论文(代表作)
[1] Hui Cao#, Ya Gao#, Bingshun Wu, Jianyu Zhang, Lianke Wang, Peifa Wei, Lijie Liu, Hang Zou*, Hongping Zhou, Zheng Zheng*, Ben Zhong Tang*. Tuning Molecular Packing by Twisting Structure to Facilely Construct Highly Efficient Solid-State Fluorophores for Two-Photon Bioimaging and Photodynamic Therapy, Adv. Funct. Mater., 2024, 2315692.
[2] Jing Wang#, Xiaona Fang#, Jiezhen Yang#, Qin Tang, Yuchen Yang, Zeng Li,Feifei Zhang, Qiang Wu*, Zhaofeng Luo*, Zheng Zheng*. Visualization of tumor-associated neutrophils in malignant ascites of ovarian cancer with aptamer-decorated AIE probes, Sens. Actuators B Chem., 2024, 405, 135385.
[3] Zheng Zheng*, Yuchen Yang, Pingping Wang, Xuexin Gou, Junyi Gong, Xiaoqian Wu, Zhiwei Bao, Lijie Liu, Jing Zhang, Hang Zou*, Lei Zheng*, Ben Zhong Tang*. A Bright Two-Photon Lipid Droplets Probe with Viscosity-Enhanced Solvatochromic Emission for Visualizing Lipid Metabolic Disorders in Deep Tissues, Adv. Funct. Mater., 2023, 2303627.
[4] Haoran Wang#, Qiyao Li#, …, Zheng Zheng*, …, Ben Zhong Tang*. Aggregation-Induced Emission (AIE), Life and Health, ACS Nano, 2023, 17, 14347-14405.
[5] Zheng Zheng*, Tianyu Yang, Dongyu Li, Hui Cao, Junyi Gong, Haixiang Liu, Chengcheng Zhou, Lijie Liu, Peifa Wei, Xinggui Gu, Ping Lu, Jun Qian*, Ben Zhong Tang*. Molecular and Aggregate Synergistic Engineering of Aggregation-Induced Emission Luminogens to Manipulate Optical/Electronic Properties for Efficient and Diversified Functions, ACS Nano, 2023, 17, 8782-8795.
[6] Zheng Zheng*#, Hequn Zhang#, Hui Cao, Junyi Gong, Mubin He, Xuexin Gou, Tianyu Yang, Peifa Wei, Jun Qian, Wang Xi*, Ben Zhong Tang*. Intra- and Intermolecular Synergistic Engineering of Aggregation-Induced Emission Luminogens to Boost Three-Photon Absorption for Through-Skull Brain Imaging, ACS Nano, 2022, 16, 6444-6454.
[7] Mubin He#, Dongyu Li#, Zheng Zheng#, Hequn Zhang, Tianxiang Wu, Weihang Geng, Zhengwu Hu, Zhe Feng, Shiyi Peng, Liang Zhu, Wang Xi, Dan Zhu, Ben Zhong Tang*, Jun Qian*. Aggregation-induced emission nanoprobe assisted ultra-deep through- skull three-photon mouse brain imaging, Nano Today, 2022, 45, 101536.
[8] Yanhong Duo*#, Meng Suo#, Daoming Zhu, Zihuang Li*, Zheng Zheng*, Ben Zhong Tang*. AIEgen-Based Bionic Nanozymes for the Interventional Photodynamic Therapy-Based Treatment of Orthotopic Colon Cancer, ACS Appl. Mater. Interfaces, 2022, 14, 26394-26403.
[9] Xinghua Yu, Ying-Chuan Zhang, Xing Yang, Ziyang Huang, Tianfu Zhang, Liusi Yang, Wenjing Meng, Xiaotong Liu, Ping Gong, Alessandra Forni, Zheng Zheng*, Bilu Liu, Pengfei Zhang*, Lintao Cai, Ben Zhong Tang*. Bonsai-inspired AIE nanohybrid photosensitizer based on vermiculite nanosheets for ferroptosis-assisted oxygen self-sufficient photodynamic cancer therapy, Nano Today, 2022, 44, 101477.
[10] Tianfu Zhang#, Jianyu Zhang#, Fu-Bing Wang#, Hui Cao, Daoming Zhu, Xiaoyu Chen, Changhuo Xu, Xueqin Yang, Wenbin Huang, Zhaoyu Wang, Jiefei Wang, Zikai He, Zheng Zheng*, Jacky W. Y. Lam*, Ben Zhong Tang*. Mitochondria-Targeting Phototheranostics by Aggregation-Induced NIR-II Emission Luminogens: Modulating Intramolecular Motion by Electron Acceptor Engineering for Multi-Modal Synergistic Therapy, Adv. Funct. Mater., 2022, 2110526.
[11] Wei He#, Zheng Zheng#, Haotian Bai*, Ling-Hong Xiong, Lei Wang, Yinghui Li, Ryan T. K.Kwok, Jacky W. Y. Lam, Qinghua Hu, Jinquan Cheng*, Ben Zhong Tang*. A Biocompatible Dual-AIEgen System without Spectral Overlap for Quantitation of Microbial Viability and Monitoring of Biofilm Formation. Mater. Horiz., 2021, 8, 1816-1824.
[12] Yanhong Duo#, Daoming Zhu#, Xiurong Sun#, Meng Suo, Zheng Zheng*, Wei Jiang*, Ben Zhong Tang*. Patient-derived microvesicles/AIE luminogen hybrid system for personalized sonodynamic cancer therapy in patient-derived xenograft models, Biomaterials, 2021, 272, 120755.
[13] Tianfu Zhang#, Zhicong Zhou#, Zheng Zheng*, Jianyu Zhang, Ying Yu, Jacky W. Y. Lam, Jonathan E. Halpert*, Ben Zhong Tang*. “Simple” AIEgens for Non‐doped Solution‐Processed OLEDs with Emission Close to Pure Red in sRGB Gamut, Adv. Photonics Res., 2021, 2100004.
[14] Daoming Zhue#, Zheng Zheng#, Guanghong Luo#, Meng Suo, Xianming Li*, Yanhong Duo*, Ben Zhong Tang*. Single injection and multiple treatments: An injectable nanozyme hydrogel as AIEgen reservoir and release controller for efficient tumor therapy, Nano Today, 2021, 37 101091.
[15] Zheng Zheng#, Haixiang Liu#, Shaodong Zhai, Haoke Zhang, Guogang Shan, Ryan T. K. Kwok, Chao Ma, Herman H. Y. Sung, Ian D. Williams, Jacky W. Y. Lam, Kam Sing Wong, Xianglong Hu*, Ben Zhong Tang*. Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens, Chem. Sci., 2020, 11, 2494-2503.
[16] Zheng Zheng#, Dongyu Li#, Zhiyang Liu, Hui-Qing Peng, Herman H. Y. Sung, Ryan T. K. Kwok, Ian D. Williams, Jacky W. Y. Lam, Jun Qian*, Ben Zhong Tang*. Aggregation-Induced Nonlinear Optical Effects of AIEgen Nanocrystals for Ultra-Deep In Vivo Bio-Imaging, Adv. Mater., 2019, 1904799.
[17] Zheng Zheng#, Tianfu Zhang#, Haixiang Liu#, Yuncong Chen, Ryan T. K. Kwok, Chao Ma, Pengfei Zhang, Herman H. Y. Sung, Ian D. Williams, Jacky W. Y. Lam, Kam Sing Wong, Ben Zhong Tang*. Bright Near-Infrared Aggregation-Induced Emission Luminogens with Strong Two-Photon Absorption, Excellent Organelle Specificity, and Efficient Photodynamic Therapy Potential, ACS Nano, 2018, 12, 8145-8159.